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The STEP-HFpEF results demonstrate a trend towards reduced incidence of AF in the study group
This is not semaglutide damages the retina so much as fast improvement can transiently worsen retinopathy in higher risk patients, which has parallels in insulin intensification
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The question behind the question is usually: "How much longer will I be able to get compounded semaglutide at this price?" The pattern we see: patients conflate three separate timelines: Patent expiration (2031-2033 for the formulations that matter) FDA shortage list removal (expected late 2026 to Q1 2027) Generic market entry (2027 for oral, 2031-2032 for injectable, assuming no patent challenges) The timeline that affects current compounded access is number 2, not number 1
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